calculate my sample size for my project with specific way. i need to figure out the salivary function as continues variable (ml/min)So I need to know the standard deviation of the variable which is the salivary function and dental caries , and I have to write the name of the paper (from where I got the number
My Null hypothesis: Integrase inhibitor have no effect on salivary hypofunction and dental caries among HIV + women on ART.
I will attched exact example for what I need . STATISTICAL ISSUES
o
Sample size calculation
Null Hypothesis._Among women seeking abortion in Nebraska, women do not
experience longer delays in obtaining an abortion if their initial request for an abortion
does not result in a referral directly to an abortion clinic.
Sample size when using a t-test
There is no delay for women seeking abortion in Nebraska when the initial
request for an abortion does not result in a direct referral to an abortion clinic
o Effect size = 7 days“ (Abortion related mortality increases by 38% for every
additional week of gestation)
Standard deviation = 7 days
Standardized effect size = 7/7 = 1
Set alpha and beta to: alpha = 0.05 and beta = 0.10
Q1 = 20% of patients initially receive referral
Q2 = 80% of patients do not initially receive referral
o Sample size = 13 (Q1) + 53 (Q2) = 66 subjects
0 0 0
We estimate that 66 participants with full data would provide 90% power to detect a delay of 7
days or more for women whose initial request for an abortion did not result in a direct referral to
an abortion clinic, assuming that 20% of patients initially receive an abortion referral. We plan
to perform a multivariate analysis to better control for confounders, therefore we will plan to
enroll double the number initially calculated in anticipation of this analysis. Data analysis will
be performed with STATA using t-tests and linear regression.
T
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